Features
From NMR to toxicology.The first draft in minutes.
Measuring is quick, the evaluation often follows days later. With CovaSketch the common analyses are ready in minutes, organised by workflow. In the sketcher or directly in your AI.
By workflow
Discovery & drug profile
From first SMILES to ADMET evaluation. Fits medicinal chemistry, hit finding and in-silico triage.
Covabasic
Molecular weight, LogP, pKa, SMILES validation: the foundations, done right.
Covachem
ADME profiles, druglikeness, molecule comparison, design suggestions.
Covabio
Sequence tools for antibodies, peptides, mRNA, siRNA and ADCs. Plus stability indicators.
Chemreason
Reaction analysis and mechanism suggestions.
Structure & binding
Proteins, binding sites, docking. When your workflow goes 3D.
Covafold
Protein folding and structure prediction. Ideal for binding-site analysis.
Covadock
Molecular docking and binding-energy estimation.
Formulation & process
From compound to stable formulation. Solubility, stability, DoE-driven optimisation.
Covasolve
Solubility prediction, miscibility, pH curves and antisolvent strategies.
Covastab
ICH stability models, Arrhenius fits, shelf-life predictions.
Covadoe
Design of Experiments with RSM, power analysis, optimisation and ready-made templates.
Covaopt
Multi-objective optimisation, robustness, drift detection, model training.
Covalnp
LNP formulation for mRNA: encapsulation, size, PDI, N/P ratio.
Toxicology & regulatory
ICH M7, Tox21, CYP450, structural alerts. Spot risks early, with an audit trail from day one.
Covatox
ICH M7 mutagenicity screening, Tox21, CYP450, structural alerts, ADMET triage.
Analytics & QC
Mass spectra, NMR, IR, UV/Vis. Identification, purity and impurity profiles from raw data.
Covams
Mass spectra, formula prediction, fragment annotation, impurity profiling.
Covanmr
NMR analysis (1D + 2D), assignment, purity, batch identification, SST.
Chromaopt
HPLC method development: column selection, gradient, retention time.
Covauv
UV/Vis quantification, dissolution, bioanalytics, auto-analysis.
Covair
IR spectra, identification, batch processes, quality check.
Platform tools
The small helpers: server status, tool discovery, feedback hooks.
Covasyn
Job management, quota lookup and platform feedback.
Free calculators
Try them without signing up
Each calculator runs the same calculation as the full version. Enter values, see the result straight away.
ICH M7 quick classification
Structural alert and statistical model in one pass, with class, mechanism and confidence.
Open calculatorMolecular formula from exact mass
Candidate formulas for a measured m/z, with mass error in ppm, RDBE and a plausibility score.
Open calculatorDrug-likeness: Lipinski, Veber, QED
Molecular weight, LogP, hydrogen bond donors and acceptors, TPSA, plus Lipinski, Veber, Ghose, QED and synthetic accessibility.
Open calculatorIsotope pattern from molecular formula
Theoretical isotope pattern with relative intensities, the cross-check for every formula assignment.
Open calculatorHPLC starting method
Column, eluents, gradient and flow as a starting point for the first injection.
Open calculator
FAQ
Frequently asked questions
Which features are in the free plan?
After signing up you test for free with a weekly allowance. Compute-heavy tools such as folding and docking use more of the allowance than simple calculations.
Does this work with our software?
With any application that supports the open MCP standard, such as Claude, ChatGPT, Cursor and VS Code. You add the access once; the docs walk you through it.
How is an analysis counted?
Simple calculations such as LogP or pKa count as one analysis. Stability fits, docking or folding count for more. The app shows the consumption per call.
What happens to my data?
Operated under GDPR. Hosted at Hetzner in Nuremberg, data kept in the EU. No training on your data.